Cancer Cell Plasticity Laboratory

Our team has established comprehensive living biobanks for breast and fallopian tube tissue to identify actionable early cellular and molecular changes associated with tumor development.

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Team news

New review published!

Shensi Shen

Drug-tolerant persister cells in cancer: the cutting edges and future directions
@Nature Reviews Clinical Oncology,2023-11

New review published! 

Shensi Shen

Immunotherapy for Recurrent Glioma-From Bench to Bedside
@Cancers ,2023-6

New article published!

Shensi Shen

Spatial patterns of the cap-binding complex eIF4F in human melanoma cells
@Comput Struct Biotechnol Journal,2023-01

New review published! 

Shensi Shen

Editorial: Non-genetic adaptive drug resistance in cancer
@Frontiers in Cell and Developmental Biology,2022-11

Research Themes

Cancer Persister Cell

Shensi Shen

Persister cells are a small sub-population of cancer cells that maintain viability under anti-cancer treatments. These cells harbor non-genetic, reversible drug-resistance phenotypes. We are interested in understanding the underlying biological mechanisms.


Adaptive metabolism

Shensi Shen

Aberrant metabolism of cancer cells presents potential therapeutic opportunities. A growing interest focuses on how to target cancer metabolism. We are interested in  metabolic rewiring in melanoma and lung cancers, paving the way to find new metabolic targets


Single cell analysis

Shensi Shen

Translating findings from single cell studies to clinical implementations of personalized medicine, paving the way to understand the heterogeneity of tumor intrinsic features, its microenvironment and tumor cell “quorum sensing” in the niche. 


Team Members

Shensi Shen

沈慎思

Shensi Shen

Principal Investigator

李开秀

Kaixiu Li

Researcher Assitant

董博

Bo Dong

PhD candidate

卢天健

Tianjian Lu

Post-doc

彭皓宁

Haoning Peng

PhD candidate

王之乐

Zhile Wang

Post-doc

王梦瑶

Mengyao Wang

Researcher Assitant

唐新璞

Xinpu Tang

Post-doc

王雨晴

Yuqing Wang

PhD candidate

陈民琪

Minqi Chen

PhD candidate

曾冬健

Dongjian Ceng

CRA

Team building.

Team building is the process of creating a team that cohesively works together towards a common goal. The importance and main purpose of team building is to create a strong team through forming bonds and connections. Creating these bonds through team building is very beneficial to organizations.

The benefits of team building include increased communication, planning skills, employee motivation, and employee collaboration.

Socializing and making friends in the workplace is one of the best ways to increase productivity in the virtual, hybrid, or in-person workplace. Not only does it increase morale in the office: it will help our team adapt to a virtual work environment more efficiently, solving issues that come up with the “new normal.” Holding a team building activity can be short and sweet, or it can be a more complex event that everyone has more time to plan for!